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In comparison with liquids, gases …

Updated on December 20, 2024
  • Are cheap!
  • Are non-toxic (He is most commonly used)
  • Do not create waste problems
  • Are pure!
    > Easier detection (low background)
  • Are clean!
    > Less fouling, downtime, and maintenance
  • Are inert
    > High temperatures possible
    > Columns are durable
  • Are non-viscous
    > Low pressures needed
  • Show high diffusion
    > Allows the use of open-tubular columns with
       relatively large column internal diameters
    > Even lower pressures needed – or much longer
       columns possible
    > High efficiencies (plate counts) or
    > Short analysis times
  • Allow easy focusing of analyte bands
    (e.g. by cooling)
    > Many injection, sample preparation,
       and hyphenation options
  • Allow near perfect GC-MS hyphenation
    > Hardly any background
    > Usually no matrix effects           
    > Electron ionization provides highly reproducible
       (searchable) spectra!
  • Allow relatively easy modulation to achieve GC×GC!
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